Material Information |
| Title: |
A Review of the Effect of Stress, Cortisol, and Toxin Induced Stress Responses on Homeostasis in Humans and Experimental Animals |
| Physical Description: |
Book |
| Language: |
English |
| Creator: |
Boissoneault, Jeffrey B. |
| Publisher: |
New College of Florida |
| Place of Publication: |
Sarasota, Fla. |
| Creation Date: |
2007 |
| Publication Date: |
2007 |
Subjects |
| Subjects / Keywords: |
Stress Psychology
Neurobiology
Biology |
| Genre: |
bibliography ( marcgt )
theses ( marcgt )
government publication (state, provincial, terriorial, dependent) ( marcgt )
born-digital ( sobekcm )
Electronic Thesis or Dissertation |
Notes |
| Abstract: |
This thesis reviews recently published literature in an attempt to characterize stress responses particularly regarding the effects of chronic stress on an organism's ability to maintain homeostasis. When a stressful stimulus is presented to an organism, the organism will respond according to Hans Selye's General Adaptation Syndrome. First, the organism will respond with alarm, a phase distinguished by the onset of an endocrine cascade that results in a state of heightened physiological arousal. Afterward, the organism will enter the resistance phase. If the resistance phase is prolonged, the organism is affected by chronic stress. This thesis emphasizes the fact that the stress response is essentially the same whether the stressor presented to the organism is directly physiological (i.e., hypoxia or a toxin/toxicant) or emotional (processed via limbic circuitry). Of particular relevance to human health, stress responses do not always result in quick resolution of emotional stressors, especially social stressors. Therefore, it is common for these stimuli to result in chronic stress, which is implicated in the onset of a number of pathologies. Methylenedioxymethamphetamine and cardiac glycosides are used to illustrate how these toxins may elicit stress responses in model organisms, including humans, rats and mice, and lower primates. These particular toxins were chosen due to their importance in global society. |
| Statement of Responsibility: |
by Jeffrey B. Boissoneault |
| Thesis: |
Thesis (B.A.) -- New College of Florida, 2007 |
| Electronic Access: |
RESTRICTED TO NCF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE |
| Bibliography: |
Includes bibliographical references. |
| Source of Description: |
This bibliographic record is available under the Creative Commons CC0 public domain dedication. The New College of Florida, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. |
| Local: |
Faculty Sponsor: McCord, Elzie |
Record Information |
| Source Institution: |
New College of Florida |
| Holding Location: |
New College of Florida |
| Rights Management: |
Applicable rights reserved. |
| Classification: |
local - S.T. 2007 B68 |
| System ID: |
NCFE003736:00001 |
|
Material Information |
| Title: |
A Review of the Effect of Stress, Cortisol, and Toxin Induced Stress Responses on Homeostasis in Humans and Experimental Animals |
| Physical Description: |
Book |
| Language: |
English |
| Creator: |
Boissoneault, Jeffrey B. |
| Publisher: |
New College of Florida |
| Place of Publication: |
Sarasota, Fla. |
| Creation Date: |
2007 |
| Publication Date: |
2007 |
Subjects |
| Subjects / Keywords: |
Stress Psychology
Neurobiology
Biology |
| Genre: |
bibliography ( marcgt )
theses ( marcgt )
government publication (state, provincial, terriorial, dependent) ( marcgt )
born-digital ( sobekcm )
Electronic Thesis or Dissertation |
Notes |
| Abstract: |
This thesis reviews recently published literature in an attempt to characterize stress responses particularly regarding the effects of chronic stress on an organism's ability to maintain homeostasis. When a stressful stimulus is presented to an organism, the organism will respond according to Hans Selye's General Adaptation Syndrome. First, the organism will respond with alarm, a phase distinguished by the onset of an endocrine cascade that results in a state of heightened physiological arousal. Afterward, the organism will enter the resistance phase. If the resistance phase is prolonged, the organism is affected by chronic stress. This thesis emphasizes the fact that the stress response is essentially the same whether the stressor presented to the organism is directly physiological (i.e., hypoxia or a toxin/toxicant) or emotional (processed via limbic circuitry). Of particular relevance to human health, stress responses do not always result in quick resolution of emotional stressors, especially social stressors. Therefore, it is common for these stimuli to result in chronic stress, which is implicated in the onset of a number of pathologies. Methylenedioxymethamphetamine and cardiac glycosides are used to illustrate how these toxins may elicit stress responses in model organisms, including humans, rats and mice, and lower primates. These particular toxins were chosen due to their importance in global society. |
| Statement of Responsibility: |
by Jeffrey B. Boissoneault |
| Thesis: |
Thesis (B.A.) -- New College of Florida, 2007 |
| Electronic Access: |
RESTRICTED TO NCF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE |
| Bibliography: |
Includes bibliographical references. |
| Source of Description: |
This bibliographic record is available under the Creative Commons CC0 public domain dedication. The New College of Florida, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. |
| Local: |
Faculty Sponsor: McCord, Elzie |
Record Information |
| Source Institution: |
New College of Florida |
| Holding Location: |
New College of Florida |
| Rights Management: |
Applicable rights reserved. |
| Classification: |
local - S.T. 2007 B68 |
| System ID: |
NCFE003736:00001 |
|