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Reactions of Magnesium and Zinc Salts with Acetol and Carbon Dioxide as Models for Catalysis by Rubisco

Permanent Link: http://ncf.sobek.ufl.edu/NCFE003942/00001

Material Information

Title: Reactions of Magnesium and Zinc Salts with Acetol and Carbon Dioxide as Models for Catalysis by Rubisco
Physical Description: Book
Language: English
Creator: Horowitz, Julie Elena
Publisher: New College of Florida
Place of Publication: Sarasota, Fla.
Creation Date: 2008
Publication Date: 2008

Subjects

Subjects / Keywords: Rubisco
Mimic
Carbon Dioxide
Genre: bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract: The ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) enzyme catalyzes the carboxylation of ribulose-1,5-bisphosphate (RuBP) during the Calvin cycle of photosynthesis. A functional model of this system may provide opportunities for the industrial synthesis of new carbon-carbon bonds while simultaneously reducing net carbon dioxide output. Previous research has shown that the magnesium-bound complex triazacyclononane-monoacetate (MgTCMA) is able to mimic the first step in the mechanism at the RuBisCO active site. Results indicated that MgTCMA helped promote a deuterium exchange reaction of acetol�s methyl and hydroxymethyl protons as confirmed by 1H-NMR spectroscopy. Subsequent research showed that the simple magnesium salt, Mg(O3SCF3)2, catalyzed the same reaction. The goal of this research was to determine if magnesium and zinc salts reacted with acetol and carbon dioxide can further model the active site of RuBisCO and result in formation of new carbon-carbon bonds. Decreases in proton resonances over time indicate that acetol is rapidly deuterated in the presence of Mg (O3SCF3)2 and Zn(O3SCF3)2 and base with multiple turnovers. However, upon the addition of carbon dioxide, no changes in 13C-NMR resonances were observed for acetol or carbon dioxide. The increases in acidity due to carbon dioxide decrease the reactivity of these systems. However, even when the basicity was increased, no reaction with carbon dioxide was observed.
Statement of Responsibility: by Julie Elena Horowitz
Thesis: Thesis (B.A.) -- New College of Florida, 2008
Electronic Access: RESTRICTED TO NCF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE
Bibliography: Includes bibliographical references.
Source of Description: This bibliographic record is available under the Creative Commons CC0 public domain dedication. The New College of Florida, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Local: Faculty Sponsor: Sherman, Suzanne

Record Information

Source Institution: New College of Florida
Holding Location: New College of Florida
Rights Management: Applicable rights reserved.
Classification: local - S.T. 2008 H8
System ID: NCFE003942:00001

Permanent Link: http://ncf.sobek.ufl.edu/NCFE003942/00001

Material Information

Title: Reactions of Magnesium and Zinc Salts with Acetol and Carbon Dioxide as Models for Catalysis by Rubisco
Physical Description: Book
Language: English
Creator: Horowitz, Julie Elena
Publisher: New College of Florida
Place of Publication: Sarasota, Fla.
Creation Date: 2008
Publication Date: 2008

Subjects

Subjects / Keywords: Rubisco
Mimic
Carbon Dioxide
Genre: bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract: The ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) enzyme catalyzes the carboxylation of ribulose-1,5-bisphosphate (RuBP) during the Calvin cycle of photosynthesis. A functional model of this system may provide opportunities for the industrial synthesis of new carbon-carbon bonds while simultaneously reducing net carbon dioxide output. Previous research has shown that the magnesium-bound complex triazacyclononane-monoacetate (MgTCMA) is able to mimic the first step in the mechanism at the RuBisCO active site. Results indicated that MgTCMA helped promote a deuterium exchange reaction of acetol�s methyl and hydroxymethyl protons as confirmed by 1H-NMR spectroscopy. Subsequent research showed that the simple magnesium salt, Mg(O3SCF3)2, catalyzed the same reaction. The goal of this research was to determine if magnesium and zinc salts reacted with acetol and carbon dioxide can further model the active site of RuBisCO and result in formation of new carbon-carbon bonds. Decreases in proton resonances over time indicate that acetol is rapidly deuterated in the presence of Mg (O3SCF3)2 and Zn(O3SCF3)2 and base with multiple turnovers. However, upon the addition of carbon dioxide, no changes in 13C-NMR resonances were observed for acetol or carbon dioxide. The increases in acidity due to carbon dioxide decrease the reactivity of these systems. However, even when the basicity was increased, no reaction with carbon dioxide was observed.
Statement of Responsibility: by Julie Elena Horowitz
Thesis: Thesis (B.A.) -- New College of Florida, 2008
Electronic Access: RESTRICTED TO NCF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE
Bibliography: Includes bibliographical references.
Source of Description: This bibliographic record is available under the Creative Commons CC0 public domain dedication. The New College of Florida, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Local: Faculty Sponsor: Sherman, Suzanne

Record Information

Source Institution: New College of Florida
Holding Location: New College of Florida
Rights Management: Applicable rights reserved.
Classification: local - S.T. 2008 H8
System ID: NCFE003942:00001

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