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OPIOID ADDICTION AND TREATMENT

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Material Information

Title:
OPIOID ADDICTION AND TREATMENT
Physical Description:
Book
Language:
English
Creator:
Husar, Anamaria
Publisher:
New College of Florida
Place of Publication:
Sarasota, Fla.
Publication Date:

Thesis/Dissertation Information

Degree:
Bachelor's ( B.A.)
Degree Grantor:
New College of Florida
Degree Divisions:
Social Sciences
Area of Concentration:
Biological Psychology
Faculty Sponsor:
Bauer, Gordon

Subjects

Genre:
bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, territorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract:
Addiction has been characterized as a chronic, relapsing disorder due to the neurobiological and behavioral modifications that occur during the addiction cycle. This review focuses on current treatment strategies available to heroin addicts and addresses the research that must be conducted to improve treatment outcome. Methadone maintenance treatment has proved to be effective in improving treatment retention. However, the pharmacokinetic and pharmacodynamic effects of methadone at opioid receptors produce respiratory depression, cognitive impairments, and tolerance. Therefore, an alternative to this approach is suggested. The unique pharmacology of buprenorphine at the mu-opioid receptor (i.e., high affinity, low intrinsic activity, and slow dissociation) results in superior safety profile, low physical dependence, and flexibility in dose scheduling compared to methadone. More recently, a combination of buprenorphine/naloxone in a 4:1 ratio (Suboxone) has been assessed with the goal of decreasing diversion and abuse associated with buprenorphine. Evidence suggests that pharmacological approaches in the treatment of heroin addiction are most effective when used in tandem with psychosocial interventions, including 12-step programs and cognitive behavioral therapy. Although buprenorphine/naloxone is a novel pharmacotherapeutic, this combination medication is a promising corrective treatment for opioid addiction.
Statement of Responsibility:
by Anamaria Husar
Thesis:
Thesis (B.A.) -- New College of Florida, 2014
General Note:
RESTRICTED TO NCF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE
Bibliography:
Includes bibliographical references.
General Note:
This bibliographic record is available under the Creative Commons CC0 public domain dedication. The New College of Florida Libraries, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
General Note:
Faculty Sponsor: Bauer, Gordon

Record Information

Source Institution:
New College of Florida
Holding Location:
New College of Florida
Rights Management:
Applicable rights reserved.
Resource Identifier:
Classification:
S.T. 2014 H87
System ID:
AA00024753:00001

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